Zafatek Tablets 100mg 糖尿病治疗剂 曲格列汀琥珀酸盐片 [0114987123155288]

Zafatek Tablets 100mg 糖尿病治疗剂 曲格列汀琥珀酸盐片 [0114987123155288]

Price: US$378.00(tax included)

List Price: US$454.00

Weight: 100g

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Item description

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Zafatek Tablets 100mg
 Active ingredient:
Trelagliptin succinate
 Dosage form:
pale red oval tablet, major axis: 11.0 mm, minor axis: 5.6 mm, thickness: about 3.8 mm
 Print on wrapping:
(表)糖尿病治療薬 ザファテック錠 100mg D389 週1回のむ薬です,(裏)糖尿病治療薬 ザファテック錠 100mg Zafatek Tablets 100mg 週1回のむくすりです

Effects of this medicine

This medicine inhibits DPP-4, an enzyme degrading incretin hormones that maintain a constant level of blood glucose, to stimulate insulin secretion when blood glucose is elevated and thereby to improve blood glucose control.
It is usually used to treat type II diabetes mellitus.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have ketosis, diabetic coma or precoma, type 1 diabetes mellitus, severe infection, an injury, renal disorder, pituitary abnormality or adrenal disease.
    If you are in a pre- or post-operative status or weakened.
    If you do not consume an adequate diet.
    If you have been doing vigorous exercise or taking a large amount of alcohol.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 1 tablet (100 mg of trelagliptin) at a time, once a week, on a fixed day of the week. The dosage may be reduced according to the degree of renal function in patients with moderate or severer renal dysfunction. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible and then follow your regular weekly dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Strictly follow the instructions on dietary/exercise therapy.
  • This medicine may cause hypoglycemia. Pay close attention to operating dangerous machinery, such as working at heights or driving a car. Tell your family members and other people around you that you are taking this medicine.
  • When hypoglycemia symptoms occur, take an adequate amount of sugar (e.g., sugar, glucose, soft drinks). If you are taking the medicine concomitantly with an α-glucosidase inhibitor (medicines which delay absorption of sugar such as voglibose and acarbose), ingest glucose in case of any hypoglycemic symptoms.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include nasopharyngitis, rash and itching. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • cold sweat, hungry feeling, trembling of limbs [hypoglycemia]
  • blister, erosion, red rash [pemphigoid]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

成分与分量 

曲格列汀琥珀酸盐/trelagliptin succinate/トレラグリプチンコハク酸塩
100mg/片

 

 

 

剂型或形状 

片剂

 

 

功效

武田製薬:全球首款一周口服1粒II型糖尿病药物。
Trelagliptin(曲格列汀)是一种每周一次的二肽基肽酶IV(DPP-4)抑制剂,通过选择性、持续性抑制DPP-4,控制血糖水平。DPP-4是一种酶,能够引发肠促胰岛素(胰高血糖素样肽-1(GLP-1)和葡萄糖依赖性促胰岛素多肽(GIP))的失活,而这2种肠降胰岛素在血糖调节中发挥着重要作用。抑制DPP-4,能够增加血糖水平依赖性胰岛素分泌,从而控制血糖水平!Trelagliptin NDA的提交,是基于在日本2型糖尿病患者中开展的数个III期临床试验的疗效和安全性数据!Trelagliptin的疗效在所有试验中均得到了证实,同时具有良好的安全性和耐受性。Trelagliptin每周给药1次便可有效控制血糖水平,从而改善患者的胰岛素用药依从性!️DPP-4抑制剂是首类可通过提高机体自身能力控制血糖水平的新型2型糖尿病药物!可用作单药,也可与其它口服降糖药联用。其作用机制独特,具有不产生低血糖、不引起体重增加,以及副作用小等独特优势,引起胃肠道不良反应的发生率很低。

 

 


用药提示:
简单来说它的作用是修复自身分泌胰岛素的功能,有可能使糖尿病可逆,那么具体是否要和其它降糖药一起服用呢?这个要看患者的病情 ,如果是初期不严重的话,可以不吃降糖药,但要观察血糖,一旦高,马上吃降糖药;如果糖尿病史很久了,也一直在用降糖药的话,不能一下子断药,要一边观察血糖,一边减药量,直到彻底断掉降糖药。另外需要注意的是,用这个药也需要患者注意饮食习惯的,如果习惯暴饮暴食的话,治疗效果可能不佳。


 

用法用量

每周服用一片,固定在每周的同一天,早饭前半小时服用 。

 

 

副作用

可能出现的副作用鼻咽炎,皮疹,瘙痒等。 
如果出现冷汗,空腹感,手脚发抖可能是低血糖的初期症状。
如果您注意到这种症状,请咨询您的医生或药剂师。

 

 

使用上请注意

以前使用过同类药物,已经有过敏症状,如瘙痒,皮疹者慎用 。
怀孕或哺乳者慎用。
正在使用其他药物(可能加强或弱化相互的作用,包括非处方药品)。

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