1. Home
  2. > Prescription Medicine
  3. > DIQUAS ophthalmic solution 3% 干眼症 地夸磷索四钠滴眼液

DIQUAS ophthalmic solution 3% 干眼症 地夸磷索四钠滴眼液 [0114987084170108]

DIQUAS ophthalmic solution 3% 干眼症 地夸磷索四钠滴眼液 [0114987084170108]

Price: US$111.20(tax included)

List Price: US$133.50

Weight: 130g

Available
Quantity:
Contact Us
Wish List

Item description

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
DIQUAS ophthalmic solution 3%
　Active ingredient:
Diquafosol sodium
　Dosage form:
limpid and colorless, ophthalmic solution, 5mL, (bottle) clear and colorless, (cap) clear bright blue
　Print on wrapping:
 

Effects of this medicine

This medicine improves keratoconjunctival epithelial disorder by promoting secretion of mucin and water as components of tears, thereby improving the tear film conditions.
It is usually used to treat dry eye.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you wear contact lenses.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, apply 1 drop at a time, 6 times a day. Strictly follow the instructions.
  • Before applying, wash your hands thoroughly with soap and running water. Pull down your lower eyelid so that the dropper tip does not touch eye or eyelashes and apply the medicine. After applying, do not blink and keep your eyes closed for a while. Wipe off any excess liquid with a clean gauze or tissue. If you need to apply other eye drops at the same time, wait more than 5 minutes.
  • If you miss a dose, apply the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should not apply two doses at one time.
  • If you accidentally apply more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop applying this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include stinging eyes, eye mucus, bloodshot eyes, eye pain, itchy eyes, foreign body sensation in eyes, ocular discomfort, lacrimation, and blepharitis (erosion of eyelids). If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
No pertinent entries.
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of reach of children. Store away from direct sunlight and heat.
  • Discard the remainder. Do not store them.

简介：

英文药名：DIQUAS（Diquafosol Sodium ophthalmic solution 3%）

中文药名：地夸磷索四钠滴眼液3%

生产厂家：参天制药
Diquas（Diquafosol Sodium）是全球获准上市的首个P2Y2受体激动剂滴眼液，耐受性好，可长期使用.
批准上市日期：2011年11月


商標名
DIQUAS ophthalmic solution 3%
一般名
ジクアホソルナトリウム（Diquafosol Sodium）

 

 

药理学
作用机序
1. 通过作用于P2Y2受体的杯状细胞的膜和结膜上皮细胞，从而提高细胞内钙离子浓度，Diquafosol钠促进粘蛋白和水的分泌。
2.泪液分泌促进作用，包括粘蛋白
(1)在（大鼠和兔）正常动物，并从结膜细胞促进黏液分泌和眼泪Diquafosol钠单一灌输的分泌。
(2) 在大鼠干眼模型，并通过Diquafosol钠单次滴眼促进泪液分泌。另外，粘蛋白在结膜组织的量增加了反复滴眼。
3.改善角膜上皮障碍
一天Diquafosol钠，在4周的重复灌注以浓度依赖性方式提高6倍，在大鼠干眼症模型角膜上皮病症表明在1％或更高的最大效果。另外，在1％的2周重复滴注，显示最大的改善，每天在6次以上.

 

 


适应症:
本品用于干眼症

 

 


剂量与用法
每天6次/滴，每次一滴

 

 


制造厂商
参天制药有限公司

 

 


产品特点及上市
3%地夸磷索四钠(Diquafosol sodium)滴眼液是参天和Inspire两制药公司联合开发的产品(商品名：Diquas ジクアス点眼液3％)，用于治疗干眼病。2010年在日本上市。
Diquas是全球获准上市的首个P2Y2受体激动剂滴眼液，以新作用机制治疗干眼病：通过促进水和黏蛋白分泌改善干眼病症状，使泪膜更接近正常状态。在日本的临床研究中，未发现严重的眼部和全身性不良反映。Diquas用药的耐受性好，故可用于长期治疗干眼病症状。

Facebook Comments

Reviews

0 reviews